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- Marie Curie -

"Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less."


Ahmed D, Al-Daraawi M, Cassol E. Innate sensing and cellular metabolism: role in fine tuning antiviral immune responses. J Leukoc Biol. 2023 Feb 1;113(2):164-190. doi: 10.1093/jleuko/qiac011.

Ahmed D, Humphrey A, Roy D, Sheridan ME, Versey Z, Jaworski A, Edwards A, Donner J, Abizaid A, Willmore W, Kumar A, Golshani A, Cassol E. HIF-1α Regulation of Cytokine Production following TLR3 Engagement in Murine Bone Marrow-Derived Macrophages Is Dependent on Viral Nucleic Acid Length and Glucose Availability. J Immunol. 2021 Dec 1;207(11):2813-2827. doi: 10.4049/jimmunol.2001282.

Gajanayaka N, Dong SXM, Ali H, Iqbal S, Mookerjee A, Lawton DA, Caballero RE, Cassol E, Cameron DW, Angel JB, Crawley AM, Kumar A. TLR-4 Agonist Induces IFN-γ Production Selectively in Proinflammatory Human M1 Macrophages through the PI3K-mTOR- and JNK-MAPK-Activated p70S6K Pathway. J Immunol. 2021 Nov 1;207(9):2310-2324. doi: 10.4049/jimmunol.2001191.

Allen CH, Ahmed D, Raiche-Tanner O, Chauhan V, Mostaço-Guidolin L, Cassol E, Murugkar S. Label-free two-photon imaging of mitochondrial activity in murine macrophages stimulated with bacterial and viral ligands. Sci Rep. 2021 Jul 7;11(1):14081. doi: 10.1038/s41598-021-93043-9.

Versey Z, da Cruz Nizer WS, Russell E, Zigic S, DeZeeuw KG, Marek JE, Overhage J, Cassol E. Biofilm-Innate Immune Interface: Contribution to Chronic Wound Formation. Front Immunol. 2021 Apr 9;12:648554. doi: 10.3389/fimmu.2021.648554.

Ali H, Caballero R, Dong SXM, Gajnayaka N, Vranjkovic A, Ahmed D, Iqbal S, Crawley AM, Angel JB, Cassol E, Kumar A. Selective killing of human M1 macrophages by Smac mimetics alone and M2 macrophages by Smac mimetics and caspase inhibition. J Leukoc Biol. 2021 Oct;110(4):693-710. doi: 10.1002/JLB.4A0220-114RR.

Ahmed D, Roy D, Jaworski A, Edwards A, Abizaid A, Kumar A, Golshani A, Cassol E. Differential remodeling of the electron transport chain is required to support TLR3 and TLR4 signaling and cytokine production in macrophages. Sci Rep. 2019 Dec 11;9(1):18801. doi: 10.1038/s41598-019-55295-4.

Ahmed D, Jaworski A, Roy D, Willmore W, Golshani A, Cassol E. Transcriptional Profiling Suggests Extensive Metabolic Rewiring of Human and Mouse Macrophages during Early Interferon Alpha Responses. Mediators Inflamm. 2018 Jul 25;2018:5906819. doi: 10.1155/2018/5906819. eCollection 2018.

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