top of page

- Marie Curie -

"Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less."



Ahmed D, Roy D, Jaworski A, Edwards A, Abizaid A, Golshani A and E Cassol. Differential repurposing of
mitochondrial function is required to support TLR3 and TLR4 signaling and cytokine production in
macrophages. Scientific Reports. 2019. Under revision. doi:


Ahmed D, Roy D and E Cassol. Examining Relationships between Metabolism and Persistent Inflammation in HIV Patients on Antiretroviral Therapy. Mediators Inflamm. 2018 Sep 27;2018:6238978.

Ahmed D, Jaworski A, Willmore W, Golshani A and E Cassol. Transcriptional profiling identifies extensive metabolic rewiring of human and mouse macrophages during early type I interferon responses. Mediators Inflamm. 2018 Jul 25;2018:5906819.


Kazmirchuk T, Dick K, Burnside D, Barnes B, Moteshareie H, Hajikarimlou M, Omidi K, Ahmed D, Low A, Lettl C, Hooshyar M, Schoenrock A, Pitre S, Babu M, Cassol E, Samanfar B, Wong A, Dehne K, Green J and A Golshani. Designing Anti-Zika Virus Peptides Derived from Predicted Human-Zika Virus Protein-Protein Interactions. Journal of Computer-Aided Molecular Design. Comput Biol Chem. 2017. Dec;71:180-187.

Ahmed D and E Cassol. Role of Immunometabolism in Type I IFN responses: Implications for tumour immunology and treatment. Cancer Letters. 2017 Nov 28;409:20-29.


Cassol E, Rossouw T, Malfeld S, Mahasha P, Slavik T, Seebregts C, Bond R, du Plessis J, Janssen C, Roskams T, Nevens F, Alfano M, Poli G and S van der Merwe. CD14+ macrophages that accumulate in the colon of African AIDS patients express pro-inflammatory cytokines and are responsive to lipopolysaccharide. BMC Infectious Diseases 2015 Oct 17; 15:430.

Cassol E, Misra V, Dutta A, Morgello S, Kirk G, Mehta S, and Gabuzda D. Altered monoamine and acylcarnitine metabolism in HIV-positive and HIV-negative subjects with depression. J Acquir Immune Defic Syndr. 2015 May 1; 69(1):18-28.


Cassol E, Misra V, Dutta A, Morgello S, and Gabuzda D. CSF Metabolomics Reveals Altered Waste Clearance and Accelerated Aging in HIV Patients with Neurocognitive Impairment. AIDS. Jul 17, 2014; 28(11): 1579–1591.

Malherbe G, Steel HC, Cassol S, de Oliveira T, Seebregts CJ, Anderson R, Cassol E, and Rossouw TM. Circulating biomarkers of immune activation distinguish viral suppression from nonsuppression in HAART-treated patients with advanced HIV-1 subtype C infection. Mediators Inflamm. 2014:198413

bottom of page